The Invention of the Asthma Inhaler
The Inspiration
In 1955, a 13-year-old girl named Susie Maison posed a simple question to her father, George L. Maison, a pharmacologist: “Why can’t my asthma medicine come in a spray can like hairspray?”
The Inventor
Maison, who had a background in innovation, took his daughter’s suggestion to heart. As president of Riker Laboratories, he assigned lead chemist Irving Porush to explore the possibility of a pressurized inhaler device.
The Innovation
Porush, working with cosmetics technicians from Rexall Drugs (Riker’s parent company), utilized expertise in propellants and aerosols. He also incorporated a recently patented metering valve that could deliver precise amounts of atomized liquid. Within two months, Porush had developed the first metered-dose inhaler (MDI).
FDA Approval
In March 1956, the Food and Drug Administration (FDA) approved two new aerosol drugs for asthma, along with Porush’s MDI device.
Impact on Asthma Treatment
The MDI revolutionized asthma treatment. It was more convenient and effective than previous methods, such as nebulizers and “asthma cigarettes.” Today, pharmaceutical inhalers account for over $36 billion in global sales annually, and millions of people worldwide rely on them every day.
Legacy of Innovation
The asthma inhaler is a testament to the power of innovation. It emerged from a simple question and the collaboration of scientists, engineers, and technicians. Its impact on the lives of asthma sufferers has been profound, improving their quality of life and empowering them to manage their condition effectively.
Timeline of Key Events
- 1955: Susie Maison suggests an asthma inhaler in a spray can.
- 1956: Irving Porush develops the first metered-dose inhaler (MDI).
- 1956: FDA approves two new aerosol drugs for asthma and the MDI device.
- Present: Pharmaceutical inhalers are widely used for asthma treatment, with global sales exceeding $36 billion annually.
Additional Information
- How MDIs Work: MDIs deliver medication directly to the lungs through a pressurized aerosol. They typically contain a propellant, a medication, and a metering valve that controls the dose.
- Types of MDIs: There are two main types of MDIs: pressurized MDIs (pMDIs) and dry powder inhalers (DPIs). pMDIs use a propellant to create a mist of medication, while DPIs use the patient’s breath to disperse the medication.
- Asthma Management: Inhalers are an essential part of asthma management. They can help prevent and relieve asthma attacks, reduce inflammation, and improve lung function.
